Myelination is the process from which the axons of neurons are covered by myelin. This forms a multilaminar lipoprotein membrane that facilitates the conduction of the action potential. In the central nervous system (CNS), the myelin sheath is produced by glial cells called oligodendrocytes. Myelinated axon fibers and cells of the oligodendritic lineage largely constitute the white matter of the brain. Particularly in mammals, it is established as a process that occurs mostly in early postnatal stages and ends in the course of juvenile development. However, studies in recent years have shown dynamic changes in the microstructure of white matter in adulthood, in response to perceptual stimuli, experience, and various types of learning. Our research group is interested in determining the epigenetic mechanisms responsible for the activation of important genes for the myelination process in the murine model.